06-P001 Teratogenic effects of Adriamycin chemotherapeutic in the placenta and fetuses of Wistar rats
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06-P001 Teratogenic effects of Adriamycin chemotherapeutic in the placenta and fetuses of Wistar rats
The Doxorubicin hydrochloride, popularly known as Adriamycin, is among the most antitumoral drugs used in oncology practice. This is a glycosidic antibiotic from the anthracycline group, which acts directly on the G2/M period, leading to cell death. This study aimed at analyzing placental alteration and congenital malformations in Wistar rats fetuses who were exposed to the chemotherapeutic. Tw...
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ژورنال
عنوان ژورنال: Mechanisms of Development
سال: 2009
ISSN: 0925-4773
DOI: 10.1016/j.mod.2009.06.227